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As the college football season heats up, fans are treated to a thrilling lineup of marquee matchups on September 19, 2026. From a David-and-Goliath clash in the Pacific Northwest to a nail-biting showdown in South Bend, the gridiron promises to deliver excitement and intrigue. Let's dive into these games and what makes them worth watching.

The Eastern Washington Eagles fly into Washington to take on the Washington Huskies in a matchup that pits underdog spirit against powerhouse prowess. Our model gives Washington an 80% chance to win, predicting a 31.3 to 10.4 victory over Eastern Washington. The Huskies, led by quarterback Demond Williams, are expected to dominate both through the air and on the ground. Williams is projected to throw for 250.1 yards and nearly three touchdowns, with his dual-threat ability adding another 40 rushing yards to his stat line.
On the other side, Eastern Washington's Nate Bell will look to challenge the Huskies' defense, projected to pass for 180.8 yards. However, the Eagles face a daunting task against a Washington team that's been a fortress at home. Check out our full game prediction here as the Huskies aim to cover a hefty Vegas spread of -42.5.
In what could be the weekend's most closely contested battle, the Spartans of Michigan State take on the Fighting Irish of Notre Dame. The simulation is calling this one nearly even, with Michigan State barely edging out a 27.2 to 26.7 predicted win. Quarterback Alessio Milivojevic is expected to lead the charge for the Spartans with 264.6 passing yards and 2.6 touchdowns. Not to be outdone, Notre Dame’s CJ Carr is projected to pass for 284 yards and over three touchdowns, making this an aerial duel to remember.
Both teams have potent offenses, and with Vegas setting a high over/under at 53.5, this game promises fireworks. Will Michigan State's slight edge in the simulations translate to the field? Dive deeper into our predictions as these storied programs clash.
Traveling to the heartland, the Tulane Green Wave faces a formidable opponent in the Kansas State Wildcats. Kansas State is the favorite, with a 77% likelihood to win and a projected score of 37.4 to 18.6. The Wildcats' Avery Johnson is set to be a key figure, throwing for 213 yards and three touchdowns while adding another 48.7 rushing yards. Rodney Fields Jr. provides a strong ground game, projected to rush for nearly 74 yards.
Tulane’s Zeon Chriss-Gremillion aims to keep the Green Wave competitive, with a forecast of 265.3 passing yards and over two touchdowns. Can Tulane disrupt Kansas State's plans and make a statement on the road? Explore the full breakdown here.
As these teams prepare for battle, remember that detailed projected player stats for all games are available exclusively to GameSim+ subscribers. Learn more and subscribe to get the most comprehensive insights.